Affliction
A summary of the case histories published by Amatus Lusitanus (1511–1568) in his Centuriae1.
| Identification | Clinical Description | Outcome |
| M, adult | ‘Melancholy’, headache (‘sincciput’) | Full recovery |
| M, 27 years | Headache, fever, stupor, seizures | Death in 48 h |
| F, child | Right temporal fracture with bone depression | Full recovery |
| F, adult | Fever, headache, delirium and agitation (‘possession’) post-partum | Recovery after 1 month |
| F, 30 years | ‘Mania’ from excessive hair washing and sun exposure | Full recovery |
| F, 11 years | Obesity, ‘sanguine’. Acute right hemiparesis | Death within 1 month |
| F, 20 years | Menstrual retention, speech difficulties, headache | Full recovery |
| M, 12 years | Groaning and bruxism during sleep | Full recovery |
| M, child | Cranial horn with encephalic substance inside | Death after removal |
| M, adult | Fever and headache after killing a snake | Death in 10 days |
| M, 30 years | Vertigo, loss of appetite, gastric pain | Full recovery |
| Newborn, 15 days | Soft head tumour | Full recovery in 3 days |
| M, 48 years | Extracranial abscess with bone invasion | Full recovery |
| M, 50 years | Ischiatic pain, loss of movement in the legs | Full recovery in 3 days |
| F, 8 years | Low fever, T10 gibbus spinal deformity, lower left quadrant pain | Partial recovery, spinal deformity |
| M, 25 years | Syphilis, right facial paralysis | Full recovery after malaria |
| M, adult | Lumbar and sciatic pain | Full recovery |
| M, 6 years | Occipital trauma with fracture, vomiting and loss of consciousness | Full recovery |
| Child, 9 years | Uncharacterized seizures after leg wound | Full recovery in 2 months |
| F, adult | Facial paralysis during pregnancy. Post-partum right hemiparesis and generalized seizures | Death within days |
| M, fifth decade | Emprostothonus | Not mentioned |
| M, young | Urinary incontinence after spinal trauma | Full recovery |
| M, young | Catalepsis | Full recovery |
| F, 18 years | Fever, lethargy, confusion (‘catochos’) | Full recovery after 20 days |
| M, 5 years | Occipital trauma followed by lethargy and left hemiparesis | Full recovery in 1 month |
| F, 34 years | Fever, lethargy – (‘caros’ or ‘subet’) | Death in few days |
| F, adult | Fever, lethargy, somnolence | Full recovery after 8 days |
| M, adult | Fainting after seeing/smelling roses | Recovery |
| F, adult | Post-partum depression | Full recovery in 1 month |
| M, 16 years | Sunstroke followed by agitation, ‘mania’ and fever | Recovery after 25 days |
| M, adult | Post-purging fever and agitation | Full recovery after 1 month |
| M, adult | ‘Melancholy’ | Recovery after 2 months |
| M, adult | ‘Mania’ after wound closure | Full recovery |
| F, adult | Syphilitic neck tumour with recurrent nerve paralysis | Loss of speech |
| F, 14 years | ‘Double tertian' fever followed by lethargy or ‘caros’ | Full recovery in 15 days |
| M, adult | Severe head wound from sword fight | Full recovery after 50 days |
| F, under 20 years | Fainting after bad news | Not described |
| M, adult | Fever, headache and disturbed sleep | Full recovery |
| M, adult | Headache, insomnia | Full recovery |
| M, 35 years | Intense bilateral orbital pain after traumatic perforation of left eye | Full recovery |
| M, adult | Back pain after fall from horse | Full recovery |
| M, 8 years | Fall from high window, coma for 2 days | Full recovery |
| M, child | Left hemiparesis and seizures | Death within hours |
| M, adult | ‘Melancholy’, pre-prandial headache | Full recovery |
| M, adult | Headache | Not described |
| M, 9 years | Fall from window, multiple head contusions and fractures | Death in 3 days |
| M, 12 years | Right temporal head injury, severe headache | Recovery after 30 days |
| M, 20 years | Hallucinations | Full recovery |
| M, adult | Obsessive love | Full recovery |
| M, 14 years | Chronic headache | Full recovery |
| M, adult | Fever, headache, thirst, delirium | Slow recovery |
| M, adult | Sunstroke | Full recovery |
| M, adult | Cranial sword wound | Partial recovery, with ‘loss of reason' |
| F, adult | Anxiety, sighing, agitation, loss of appetite | Not reported |
| M, 3 years | Prolonged generalized seizures | Prolonged post-ictal hemiparesis |
| M, 70 years | ‘Apoplexy’ and sudden coma | Immediate death |
| M, 2 years | Seizures, ‘horrendous look and turbid eyes', motor retardation | Resolution of seizures? |
| M, 43 years | Fever, severe headache | Not reported |
| M, adult | ‘Melancholy’ | Full recovery after 22 days |
| F, 13 years | Fever, mental disturbances, ‘alienation’, thirst | Recovery after 4 months |
| M, 35 years | ‘Melancholy’ | Full recovery after 40 days |
| M, adult | Left ear intense pain followed by facial paralysis | Partial recovery |
| M, 35 years | Chronic pulsating headache, insomnia | Full recovery after 40 days |
| M, 4 years | Left-handedness | Full recovery |
| M, 8 years | Purulent ear infection followed by painful ‘head tumour', fever, local bone invasion | Seizures after surgery, death the next day |
| M, 40 years | Facial paralysis, loss of sensation in the face | Full recovery in 1 month |
| F, young | Scrofula, followed by spinal gibbus deformity | Not mentioned |
| M, 2 years | Occipital tumour, followed by left arm paralysis, strabismus and fever | Death in 8 days |
| F, 18 years | ‘Melancholy’, prolonged seizures with loss of feeling and left arm paralysis | Full recovery |
| M, 40 years | Right cranial (‘sincciput’) tumour. Headache and fever | Full recovery |
| F, adult | Depression during pregnancy | Full recovery |
| M, 75 years | Episodic speech disturbance, syncope with fall | Full recovery |
| M, 2 years | Fever, paralysis, loss of speech and hearing | No change after 50 days |
| M, 34 years | Syphilis, headache, vertigo and deafness | Worsening |
| F, adult | Anguish, depression, amenorrhea | Full recovery |
| M, adult | Syphilis, followed by dementia and delusions | ‘Recovery’ after sham surgery |
| M, 20 years | ‘Melancholy’ | Full recovery |
| M, adult | Lumbar and sciatic pain | Full recovery |
| M, 38 years | Vertigo, blurred vision, headache, tinnitus, loss of smell, nausea | Recovery after 40 days |
| M, adult | Multiple head-wounds and fractures | Not mentioned |
| F, adult | Fainting after bad news, ‘melancholy’ | Recovery |
| F, adult | Post-partum headache and fever | Full recovery |
| M, adult | Post-vomiting headache and dizziness | Full recovery |
| F, 54 years | Opistothonus, trismus, intense pain | Recovery in a month |
| M, 30 years | Chronic lower limb atrophy and muscle spasms | No recovery |
| M, young | Fever, agitation and delirium, followed by torpor | Recovery after 20 days |
| M, adult/M, adult | Occipital wound with loss of brain parenchyma/'Sincciputal' wound | Loss of memory (‘occiput’) vision (‘sincciput’) |
| F, 40 years | Sadness, overeating, disturbed sleep, ‘melancholy’ | Not mentioned |
| M, 20 years | ‘Tertian fever', somnolence, coma (‘subet’), exanthema, throat ulcerations | Full recovery |
| F, adult | Dog bite, followed by anguish, thirst, satyriasis, hydrophobia and disturbed behaviour | Death after 7 days |
| F, 27 years | Blindness, deafness and amenorrhea after head aggression | No recovery |
| M, adult | Bi-temporal headache, constipation, cough, ascites | Death |
| M, adult | Back pain from weight-lifting | Recovery |
| 5 adults | Rabies from cat bite | Death |
| M, 46 years | Nail puncture on the foot, followed by opisthotonus and muscle spasms | Death after 2 days |
| M, adult | Headache | Full recovery |
| M, adult | Vertigo | Full recovery after 5 days |
| M, adult | Gibbous dwarfism, ‘melancholy’, severe headache | Death |
| F, 50 years | Amenorrhea | Not mentioned |